This research focuses on using state of the art knowledge on nanoparticle-based technology aiming at improving nanocarrier system in an innovative way by:

1. Using Doxorubicin (DOX) and Paclitaxel (PTX) drugs for a synergistic therapeutic effect
2. Targeting melanoma by using antigen PMEL17, thus diminishing healthy tissue toxicity
3. Employing a mechanism of drug release, switched on by the acidic intracellular pH, thus ensuring delivery of the drugs only after cellular internalization